abstract：BACKGROUND:The use of permanent hair dyes exposes hairdressers to contact allergens such as p-phenylenediamine (PPD), and the preventive measures are insufficient. OBJECTIVES:To perform an in vivo test to study the protective effect of gloves commonly used by hairdressers. PATIENTS/MATERIALS/METHODS:Six gloves from S...

journal_title：Contact dermatitis

authors： Antelmi A,Young E,Svedman C,Zimerson E,Engfeldt M,Foti C,Bruze M

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:Healthcare workers are occupationally exposed to various allergens in protective gloves, surface or instrument disinfectants, drugs, and skin care products. An increased prevalence of sensitization to thiurams, glutaraldehyde, formaldehyde and glyoxal in nurses with occupational contact dermatitis (OCD) has ...

journal_title：Contact dermatitis

authors： Molin S,Bauer A,Schnuch A,Geier J

更新日期：2015-03-01 00:00:00

abstract：:Allergic contact dermatitis affects a worrying proportion of the general population. The mechanisms underlying this chemical-triggered delayed-type hypersensitivity are still not fully understood. In recent years, basic research has shown that the immune system reacts to contact allergens by activation of signalling p...

journal_title：Contact dermatitis

authors： Martin SF

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Chromium-tanned leather articles currently constitute the most important cause of contact allergy to chromium in Denmark. A regulation on the content of hexavalent chromium in leather was adopted in November 2013 by the EU member states. OBJECTIVES:To characterize patients with chromium allergy and their di...

journal_title：Contact dermatitis

authors： Bregnbak D,Thyssen JP,Zachariae C,Johansen JD

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:On skin contact, nickel accumulates in the stratum corneum, where it is probably bound to proteins and amino acids. One probable contributor is filaggrin, which binds nickel avidly. Filaggrin gene (FLG) null mutations lead to a complete lack of filaggrin production from the affected allele, and have been ass...

journal_title：Contact dermatitis

authors： Ross-Hansen K,Johansen JD,Vølund A,Menné T,Thyssen JP

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND/OBJECTIVES:Environmental exposure and personal susceptibility both contribute to the development of hand eczema. In this study, we investigated the effect of loss-of-function mutations in the filaggrin gene (FLG), atopic dermatitis and wet work exposure on the development of hand eczema in apprentice nurses....

journal_title：Contact dermatitis

authors： Visser MJ,Verberk MM,Campbell LE,McLean WH,Calkoen F,Bakker JG,van Dijk FJ,Bos JD,Kezic S

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Alkyl glucosides were not expected to have a sensitizing potential at the concentrations to be used in finished consumer products; however, several contact allergy cases have been published. OBJECTIVES:To report on the patients suffering from allergic contact dermatitis caused by alkyl glucosides observed i...

journal_title：Contact dermatitis

authors： Gijbels D,Timmermans A,Serrano P,Verreycken E,Goossens A

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:The evidence on the safety of topical preparations containing botanical extracts is limited. OBJECTIVES:To assess (i) the use of botanically derived compounds in a large population, (ii) the incidence of cutaneous side-effects, and (iii) the diagnostic usefulness of patch testing. METHODS:A questionnaire w...

journal_title：Contact dermatitis

authors： Corazza M,Borghi A,Gallo R,Schena D,Pigatto P,Lauriola MM,Guarneri F,Stingeni L,Vincenzi C,Foti C,Virgili A

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Adverse drug reactions pose an increasing diagnostic challenge in hospitals and in outpatient clinics. When consecutive or repeated allergic drug eruptions are suspected, patch testing is a useful diagnostic tool for determining the causative drugs. OBJECTIVES:The aim of the study was to identify patient ca...

journal_title：Contact dermatitis

authors： Liippo J,Pummi K,Hohenthal U,Lammintausta K

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Several instruments for the assessment of the severity of hand eczema and health-related quality of life (HR-QoL) related to hand eczema have been developed. OBJECTIVES:The aim of the present study was to evaluate the correlation between frequently used methods. METHODS:Consecutive patients with current ha...

journal_title：Contact dermatitis

authors： Agner T,Jungersted JM,Coenraads PJ,Diepgen T

更新日期：2013-08-01 00:00:00

abstract：:Although p-phenylenediamine (PPD) has been recognized as an extreme sensitizer for many years, the exact mechanism of sensitization has not been elucidated yet. Penetration and the ability to bind to proteins are the first two hurdles that an allergen has to overcome to be able to sensitize. This review is an overview...

journal_title：Contact dermatitis

authors： Pot LM,Scheitza SM,Coenraads PJ,Blömeke B

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:Reviews on irritant and allergic airborne contact dermatitis have been previously reported in the literature. MATERIALS AND METHODS:Here, we present an update based on recently published airborne-induced skin reactions. For this survey, we screened the journals Contact Dermatitis, Dermatitis, and included r...

journal_title：Contact dermatitis

authors： Swinnen I,Goossens A

更新日期：2013-04-01 00:00:00

abstract：:Background. Two readings of patch test reactions are recommended. Objectives. To evaluate the outcome of a second patch test reading of TRUE Test® allergens on D6/7 in relation to negative or doubtful reactions on D3/4. Methods. This was a retrospective investigation of patch test data from January 1992 to October 201...

journal_title：Contact dermatitis

authors： Madsen JT,Andersen KE

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Wheat protein derivatives are used in a variety of products worldwide. Gluten is commercially used 'as is' or with modifications such as hydrolysis, which is carried out to overcome its insolubility. Several cases of contact urticaria following exposure to hydrolysed wheat protein (HWP) in cosmetics or of an...

journal_title：Contact dermatitis

authors： Chinuki Y,Takahashi H,Dekio I,Kaneko S,Tokuda R,Nagao M,Fujisawa T,Morita E

更新日期：2013-02-01 00:00:00

abstract：:Nickel is used in coins because the metal has beneficial properties, including price, colour, weight, and corrosion resistance, and also because it is easy to stamp. It has often been claimed that the duration of skin contact with coins is too short to cause nickel release and dermatitis. However, it is well known by ...

journal_title：Contact dermatitis

authors： Thyssen JP,Gawkrodger DJ,White IR,Julander A,Menné T,Lidén C

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Cosensitization to nickel, cobalt and chromium occurs in the general population and in some occupational groups. OBJECTIVES:To estimate the isolated and concurrent occurrence of nickel, cobalt and chromium contact sensitization and their association with individual and occupational risk factors. PATIENTS/M...

journal_title：Contact dermatitis

authors： Rui F,Bovenzi M,Prodi A,Fortina AB,Romano I,Corradin MT,Filon FL

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Protein contact dermatitis is a frequent disorder among hand eczema patients who have occupational food contact. Knowledge about the consequences of having protein contact dermatitis is lacking. OBJECTIVES:To investigate the consequences of having occupational skin disease on the hands resulting from food h...

journal_title：Contact dermatitis

authors： Vester L,Thyssen JP,Menné T,Johansen JD

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Imidazolidinyl urea releases formaldehyde through decomposition. However, there have been few reports on the chemistry of imidazolidinyl urea in cosmetics. OBJECTIVES:The aim of this study was to characterize imidazolidinyl urea-derived compounds in cosmetics and to determine which compounds are responsible...

journal_title：Contact dermatitis

authors： Doi T,Takeda A,Asada A,Kajimura K

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Exposure to humid environments/water and prolonged glove occlusion are both believed to cause irritant contact dermatitis. OBJECTIVES:To study the effects of different forms of wet work, especially the differences between water exposure and occlusion, by using an experimental model simulating occupational w...

journal_title：Contact dermatitis

authors： Fartasch M,Taeger D,Broding HC,Schöneweis S,Gellert B,Pohrt U,Brüning T

更新日期：2012-10-01 00:00:00

abstract：:During the last 2 years, we have performed filaggrin genotyping in patients with eczema seen in our hand eczema clinic. We present pictures of healthy and diseased hands from individuals with filaggrin gene (FLG) mutations to describe a clinical entity of hand eczema. We show that xerosis and hyperkeratosis on the dor...

journal_title：Contact dermatitis

authors： Kaae J,Menné T,Carlsen BC,Zachariae C,Thyssen JP

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Bromo-3-chloro-5,5-dimethylhydantoin (BCDMH) is a chemical used as a disinfectant for recreational water. BCDMH was described as being responsible for an epidemic of irritant contact dermatitis in the UK (1983), and its sensitizing capacity was also discussed. OBJECTIVES:The aim of this study was to assess ...

journal_title：Contact dermatitis

authors： Dalmau G,Martínez-Escala ME,Gázquez V,Pujol-Montcusí JA,Canadell L,Espona Quer M,Pujol RM,Vilaplana J,Gaig P,Giménez-Arnau A

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Chromium-tanned leather footwear, which releases >3 ppm hexavalent Cr(VI), may pose a risk of sensitizing and eliciting allergic dermatitis. OBJECTIVES:To determine the content and potential release of chromium in leather footwear and to discuss the prevention of chromium contact allergy and dermatitis. ME...

journal_title：Contact dermatitis

authors： Thyssen JP,Strandesen M,Poulsen PB,Menné T,Johansen JD

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Contact allergy to cocamidopropyl betaine has been attributed to its impurities dimethylaminopropylamine and cocamidopropyl dimethylamine. OBJECTIVES:To describe patients with positive patch test reactions to cocamidopropyl betaine-related compounds in an occupational dermatology clinic. METHODS:We reviewe...

journal_title：Contact dermatitis

authors： Suuronen K,Pesonen M,Aalto-Korte K

更新日期：2012-05-01 00:00:00

abstract：:To critically review currently available methods, or methods under development (in vivo, in vitro, in silico, etc.) used in the evaluation of skin sensitization potential and their applicability in the derivation of quantitative 'safety thresholds'. ...

journal_title：Contact dermatitis

authors： Thyssen JP,Giménez-Arnau E,Lepoittevin JP,Menné T,Boman A,Schnuch A

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:The prognosis of occupational hand eczema is strongly associated with its duration, severity, and the onset of treatment. OBJECTIVES:The study was aimed at characterizing skin eruptions that might be potential precursors of occupational hand eczema, their pattern, and typical sites in a population at modera...

journal_title：Contact dermatitis

authors： Baumeister T,Uter W,Weistenhöfer W,Drexler H,Kütting B

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Corticosteroids (CS), anti-inflammatory drugs also widely used to treat various allergic diseases, may themselves give rise to immediate and delayed allergic hypersensitivity reactions. OBJECTIVES:To realise an appropriate diagnostic work-up in order to determine the CS-allergic patient's sensitization/tole...

journal_title：Contact dermatitis

authors： Baeck M,Goossens A

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Hand eczema is common in the nursing profession, and has been reported widely in various parts of the world. OBJECTIVES:The aim of this study was to determine the prevalence and severity of hand eczema among nurses working in a regional hospital in Hong Kong, as well as its psychosocial impact and any possi...

journal_title：Contact dermatitis

authors： Luk NM,Lee HC,Luk CK,Cheung YY,Chang MC,Chao VK,Ng SC,Tang LS

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Patch tests help to confirm the aetiology of the cutaneous adverse drug reactions involving delayed hypersensitivity mechanisms, but the results vary with the pattern of skin reaction and the culprit drug. OBJECTIVES:To analyse the results of patch tests in patients with cutaneous adverse drug reactions imp...

journal_title：Contact dermatitis

authors： Pereira N,Canelas MM,Santiago F,Brites MM,Gonçalo M

更新日期：2011-10-01 00:00:00

abstract：UNLABELLED:BACKGROUND. Allergens included in the European baseline series should result in positive patch test reactions in at least 1% of a patch test population. Inclusion of local anaesthetics other than benzocaine in the baseline series has previously been debated. OBJECTIVES:To investigate temporal trends of benz...

journal_title：Contact dermatitis

authors： Thyssen JP,Engkilde K,Menné T,Johansen JD

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Neurosensory irritation is a subjective phenomenon induced by a number of chemicals. Objectives. To investigate the sensory irritation induced by two organic solvents - n-octane and cumene - between two groups of volunteers, stingers and non-stingers, identified as such according to the results of a lactic a...

journal_title：Contact dermatitis

authors： Schliemann S,Antonov D,Manegold N,Elsner P

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Contact allergy to phenol-formaldehyde resins (PFRs) based on phenol and formaldehyde is not detected by a p-tertiary-butylphenol-formaldehyde resin (PTBP-FR) included in most baseline patch test series. OBJECTIVES:To investigate the rate of contact allergy to PFR-2 (a mixture of monomers and dimers from a ...

journal_title：Contact dermatitis

authors： Isaksson M,Inerot A,Lidén C,Matura M,Stenberg B,Möller H,Bruze M

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Thaumetopoea pityocampa [pine processionary moth (PPM)] is one of the most important lepidopteran agents causing urticant cutaneous reactions in humans in Mediterranean countries. This species is also expanding northwards, because of global warming. OBJECTIVES:To investigate the prevalence, distribution by ...

journal_title：Contact dermatitis

authors： Vega JM,Moneo I,Ortiz JC,Palla PS,Sanchís ME,Vega J,Gonzalez-Muñoz M,Battisti A,Roques A

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Nickel is the most common cause of contact allergy and an important risk factor for hand eczema. Visualization techniques may be powerful in showing exposures. The dimethylglyoxime (DMG) test might be used to establish skin exposure to nickel. OBJECTIVES:To develop and evaluate methods for visualization of ...

journal_title：Contact dermatitis

authors： Julander A,Skare L,Vahter M,Lidén C

更新日期：2011-03-01 00:00:00

abstract：:Hand dermatitis is a prevalent disease with an episodic, chronic character. The use of medical resources is high and is often related to reduced (work) functioning. The burden is therefore high for patients and society. Management of hand dermatitis is often unsatisfactory, and for this reason prevention is important....

journal_title：Contact dermatitis

authors： van Gils RF,Boot CR,van Gils PF,Bruynzeel D,Coenraads PJ,van Mechelen W,Riphagen II,Anema JR

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:Occlusion of the skin is a risk factor for development of irritant contact dermatitis. Occlusion may, however, have a positive effect on skin healing. No consensus on the effect of occlusion has been reached. OBJECTIVES:To investigate skin barrier response to occlusion on intact and damaged skin. METHODS:I...

journal_title：Contact dermatitis

authors： Jungersted JM,Høgh JK,Hellgren LI,Jemec GB,Agner T

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:Methylchloroisothiazolinone/methylisothiazolinone (MCI/MI) has been one of the most frequent sensitizers since the 1980s. In 2005, the use of MI alone was approved for the preservation of cosmetic and household products in the EU. Before that, MI was used in industrial products, and the first cases of isolat...

journal_title：Contact dermatitis

authors： Lundov MD,Thyssen JP,Zachariae C,Johansen JD

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Wheat protein and its derivatives can cause protein contact dermatitis (PCD), which mainly occurs in bakers. Few studies have attempted to identify the allergens responsible for wheat PCD. OBJECTIVES:The aim of this study was to identify allergenic wheat proteins in patients with wheat PCD. METHODS:Water-s...

journal_title：Contact dermatitis

authors： Matsuo H,Uemura M,Yorozuya M,Adachi A,Morita E

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:Photocontact dermatitis to Ficus carica is induced by furocoumarins present in sap. These substances are generally considered to cause phototoxic reactions. OBJECTIVES:We conducted a patch test and histopathological study of patients with phytophoto contact dermatitis from the fig tree to evaluate the mecha...

journal_title：Contact dermatitis

authors： Bonamonte D,Foti C,Lionetti N,Rigano L,Angelini G

更新日期：2010-06-01 00:00:00

abstract：:The phenomenon of 'sensitive skin' is a relatively recent complaint in which certain individuals report more intense and frequent adverse sensory effects than the normal population upon use of cosmetic (personal-care) products. Originally defined as a minority complaint, sensitive skin is now claimed by a majority of ...

journal_title：Contact dermatitis

authors： Farage MA,Maibach HI

更新日期：2010-03-01 00:00:00

abstract：:Numerous studies have investigated the prevalence and risk factors of hand eczema in the general population. These studies are of high value as they tend to be less biased than studies using clinical populations and as they are important for healthcare decision makers when they allocate resources. This study aimed to ...

journal_title：Contact dermatitis

authors： Thyssen JP,Johansen JD,Linneberg A,Menné T

更新日期：2010-02-01 00:00:00